Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11008629 | 0.91 | ALDH1A1 (0.72) | ALDH1A1POLBGAAKDM4ELMNA | |
| SCHEMBL11012408 | 0.86 | ALDH1A1 (0.78) | ALDH1A1GAAKDM4ELMNAHPGD | |
| SCHEMBL11009134 | 0.86 | ALDH1A1 (0.80) | ALDH1A1POLBGAAKDM4ELMNA | |
| SCHEMBL11010581 | 0.86 | ALDH1A1 (0.77) | ALDH1A1GAAKDM4ELMNAHPGD | |
| SCHEMBL11011188 | 0.86 | ALDH1A1 (0.75) | ALDH1A1GAAKDM4ELMNAHPGD | |
| SCHEMBL11006398 | 0.86 | ALDH1A1 (0.75) | ALDH1A1GAAKDM4ELMNAHPGD | |
| SCHEMBL11008653 | 0.84 | ALDH1A1 (0.77) | ALDH1A1GAAKDM4ELMNAHPGD | |
| SCHEMBL11012342 | 0.84 | ALDH1A1 (0.77) | ALDH1A1GAAKDM4ELMNAHPGD | |
| SCHEMBL11010388 | 0.84 | ALDH1A1 (0.74) | ALDH1A1GAAKDM4ELMNAHPGD | |
| SCHEMBL11014272 | 0.83 | ALDH1A1 (0.68) | ALDH1A1GAAKDM4ELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4507315-A | Hypoglycaemic and hypolipidaemic benzamide substituted (1H-) imidazole derivatives and compositions | MAY & BAKER LIMITED (GB) | 1985-03-26 | — | — | US | disclosed |
| US-4496568-A | Antiinflammatory thieno [2,3-c]pyridine derivatives | PACOR (FR) | 1985-01-29 | — | — | US | disclosed |