Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.69 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | YWHAG | P61981 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 4/20 | 0.39 |
| ▸ | SMARCA4 | P51532 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10726184 | 0.83 | ALDH1A1 (0.62) | GFERGAAKDM4EMEN1MAPT | |
| SCHEMBL11107477 | 0.82 | GFER (0.81) | GFERGPBAR1GAAHPGDKDM4E | |
| SCHEMBL10355571 | 0.80 | ALDH1A1 (0.59) | GFERGAAHPGDKDM4EMEN1 | |
| SCHEMBL11008608 | 0.79 | GAA (0.69) | GFERAVPR2GAAKDM4EMEN1 | |
| SCHEMBL17774801 | 0.78 | GFER (0.92) | GFERGAAKDM4EMEN1MAPT | |
| SCHEMBL11097632 | 0.77 | GFER (0.57) | GFERGPBAR1HPGDMAPTALDH1A1 | |
| SCHEMBL2774234 | 0.72 | KDM4E (0.61) | GFERGPBAR1GAAHPGDKDM4E | |
| SCHEMBL9983954 | 0.71 | GFER (0.63) | GFERGAAHPGDMEN1MAPT | |
| SCHEMBL17774580 | 0.69 | GFER (0.61) | GFERGAAMEN1MAPTTHRB | |
| SCHEMBL11125143 | 0.69 | ALDH1A1 (0.54) | GAAHPGDKDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4528294-A | Benzoyl-phenyl-piperidine derivatives | SOCIETE DE RECHERCHES INDUSTRIELLE S.O.R.I. (FR) | 1985-07-09 | — | — | US | claimed |
| EP-0069012-B1 | BENZOYL-PHENYL-PIPERIDINE DERIVATIVES, THEIR PREPARATION AND MEDICINAL USE | SOCIETE DE RECHERCHES INDUSTRIELLES S.O.R.I. (FR) | 1984-10-10 | — | — | EP | claimed |
| EP-0069012-A1 | Benzoyl-phenyl-piperidine derivatives, their preparation and medicinal use | SOCIETE DE RECHERCHES INDUSTRIELLES S.O.R.I. (FR) | 1983-01-05 | — | — | EP | claimed |