Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31259942 | 0.86 | MME (0.47) | GNPAT | |
| SCHEMBL30692727 | 0.86 | MME (0.47) | GNPAT | |
| SCHEMBL30578424 | 0.86 | MME (0.47) | GNPAT | |
| SCHEMBL10557246 | 0.85 | GNPAT (0.49) | GNPATOPRD1OPRM1OPRK1CTSC | |
| SCHEMBL29577210 | 0.84 | MME (0.47) | — | |
| SCHEMBL9667576 | 0.83 | CTSC (0.47) | CTSC | |
| SCHEMBL7277013 | 0.83 | CTSC (0.47) | CTSC | |
| SCHEMBL3881794 | 0.83 | CTSC (0.47) | CTSC | |
| SCHEMBL9666897 | 0.83 | CTSC (0.47) | CTSC | |
| SCHEMBL9672005 | 0.83 | CTSC (0.47) | CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0144290-A2 | Substituted ethylenediamine derivatives | CIBA-GEIGY AG (CH) | 1985-06-12 | — | — | EP | claimed |
| EP-0144290-A2 | Substituted ethylenediamine derivatives | CIBA-GEIGY AG (CH) | 1985-06-12 | — | — | EP | disclosed |