Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.49 |
| ▸ | CTSC | P53634 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11008491 | 0.85 | GNPAT (0.40) | GNPATCTSCOPRD1OPRM1OPRK1 | |
| SCHEMBL29670420 | 0.83 | CTSL (0.60) | OPRK1 | |
| SCHEMBL32661261 | 0.82 | OPRD1 (0.55) | OPRD1OPRM1OPRK1MME | |
| Acetic Acid SCHEMBL29391847 | 0.82 | GNPAT (0.61) | GNPATCTSCALPIPKMPTGS1 | |
| SCHEMBL8082487 | 0.82 | MME (0.63) | GNPATCTSCALPIPKMPTGS1 | |
| SCHEMBL8082492 | 0.82 | MME (0.63) | GNPATCTSCALPIPKMPTGS1 | |
| SCHEMBL14772130 | 0.82 | MME (0.63) | GNPATCTSCALPIPKMPTGS1 | |
| SCHEMBL30862466 | 0.82 | MME (0.63) | GNPATCTSCALPIPKMPTGS1 | |
| SCHEMBL30862442 | 0.82 | MME (0.63) | GNPATCTSCALPIPKMPTGS1 | |
| SCHEMBL30862464 | 0.82 | MME (0.63) | GNPATCTSCALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4863903-A | RENIN ENZYME INHIBITORS, HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1989-09-05 | — | — | US | disclosed |
| US-4719288-A | HYPOTENSIVE | CIBA-GEIGY CORPORATION (US) | 1988-01-12 | — | — | US | disclosed |
| US-4613676-A | PEPTIDES | CIBA-GEIGY CORPORATION (US) | 1986-09-23 | — | — | US | disclosed |
| EP-0143746-A2 | 5-Amino 4-hydroxy-valeryl-substituted derivatives | CIBA-GEIGY AG (CH) | 1985-06-05 | — | — | EP | disclosed |