Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11008090 | 0.77 | ALDH1A1 (0.45) | GRM5KMT2AL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL24462562 | 0.76 | KMT2A (0.50) | GRM5KMT2ALMNANAPRTP4HTM | |
| SCHEMBL16211860 | 0.73 | NAPRT (0.59) | KMT2ALMNANAPRTP4HTML3MBTL1 | |
| SCHEMBL31369148 | 0.73 | KMT2A (0.75) | KMT2ALMNANAPRTP4HTML3MBTL1 | |
| SCHEMBL87791 | 0.73 | KMT2A (0.75) | KMT2ALMNANAPRTP4HTML3MBTL1 | |
| SCHEMBL8178870 | 0.73 | KMT2A (0.46) | KMT2ALMNANAPRTP4HTML3MBTL1 | |
| SCHEMBL22551832 | 0.72 | GRM5 (0.48) | GRM5KMT2ALMNANAPRTP4HTM | |
| Charcoal, Activated SCHEMBL8358164 | 0.71 | KMT2A (0.72) | KMT2ALMNANAPRTP4HTML3MBTL1 | |
| Water SCHEMBL6228901 | 0.71 | KMT2A (0.72) | KMT2ALMNANAPRTP4HTML3MBTL1 | |
| SCHEMBL31369119 | 0.71 | KMT2A (0.72) | KMT2ALMNANAPRTP4HTML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4512991-A | 3-Acyl-2-amino-5-halo-6-(substituted)pyrazine antimicrobial compounds | MERCK & CO., INC. (US) | 1985-04-23 | — | — | US | disclosed |