Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.43 |
| ▸ | TUBB | P07437 | 3/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1744281 | 0.83 | MEN1 (0.53) | BRD4ALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL3239896 | 0.81 | MAOB (0.37) | BRD4KDM4EHPGDPTGS1PTGS2 | |
| SCHEMBL13511832 | 0.77 | MAPT (0.49) | BRD4ALDH1A1KDM4EL3MBTL1PTGS2 | |
| SCHEMBL11624499 | 0.76 | MAPT (0.51) | BRD4ALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL1742298 | 0.76 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDL3MBTL1PTGS1 | |
| SCHEMBL9186261 | 0.75 | PDE4B (0.43) | BRD4ALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL9183215 | 0.75 | SMN1; SMN2 (0.43) | BRD4ALDH1A1KDM4EHPGDL3MBTL1 | |
| SCHEMBL9183532 | 0.75 | SMN1; SMN2 (0.48) | ALDH1A1KDM4EL3MBTL1MEN1MAPK1 | |
| SCHEMBL9180769 | 0.75 | SMN1; SMN2 (0.48) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL5206468 | 0.75 | PDGFRB (0.49) | BRD4ALDH1A1KDM4EHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4515791-A | Substituted phenyl-1,2,4-triazolo[2,3-b]pyridazin-3(2H)ones as anti-asthma agents | AMERICAN CYANAMID COMPANY (US) | 1985-05-07 | — | — | US | disclosed |