Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601578 | 1.00 | EPHX2 (0.44) | EPHX2MAOAMAOBHDAC1HDAC2 | |
| SCHEMBL12315998 | 1.00 | EPHX2 (0.44) | EPHX2MAOAMAOBHDAC1HDAC2 | |
| SCHEMBL17760173 | 1.00 | EPHX2 (0.44) | EPHX2MAOAMAOBHDAC1HDAC2 | |
| SCHEMBL17760450 | 1.00 | EPHX2 (0.44) | EPHX2MAOAMAOBHDAC1HDAC2 | |
| SCHEMBL23601628 | 1.00 | EPHX2 (0.44) | EPHX2MAOAMAOBHDAC1HDAC2 | |
| SCHEMBL11098531 | 0.98 | EPHX2 (0.42) | EPHX2MAOAMAOBHDAC1HDAC2 | |
| SCHEMBL6050144 | 0.93 | TSHR (0.42) | EPHX2MAOAMAOBHDAC1HDAC2 | |
| Hydrazine SCHEMBL10768065 | 0.91 | EPHX2 (0.46) | EPHX2MAOAMAOBHDAC1HDAC2 | |
| SCHEMBL20450540 | 0.91 | EPHX2 (0.49) | EPHX2HDAC1HDAC2HDAC6HDAC8 | |
| SCHEMBL14482131 | 0.91 | EPHX2 (0.49) | EPHX2HDAC1HDAC2HDAC6HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0144290-A2 | Substituted ethylenediamine derivatives | CIBA-GEIGY AG (CH) | 1985-06-12 | — | — | EP | disclosed |