Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | DGKA | P23743 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11010488 | 0.98 | EPHX2 (0.44) | EPHX2MAOAMAOBHDAC1HDAC2 | |
| SCHEMBL12315998 | 0.98 | EPHX2 (0.44) | EPHX2MAOAMAOBHDAC1HDAC2 | |
| SCHEMBL17760450 | 0.98 | EPHX2 (0.44) | EPHX2MAOAMAOBHDAC1HDAC2 | |
| SCHEMBL23601578 | 0.98 | EPHX2 (0.44) | EPHX2MAOAMAOBHDAC1HDAC2 | |
| SCHEMBL17760173 | 0.98 | EPHX2 (0.44) | EPHX2MAOAMAOBHDAC1HDAC2 | |
| SCHEMBL23601628 | 0.98 | EPHX2 (0.44) | EPHX2MAOAMAOBHDAC1HDAC2 | |
| SCHEMBL6050144 | 0.95 | TSHR (0.42) | EPHX2MAOAMAOBHDAC1HDAC2 | |
| SCHEMBL134923 | 0.91 | EPHX2 (0.46) | EPHX2HDAC1HDAC2HDAC6TSHR | |
| SCHEMBL951742 | 0.88 | STING1 (0.37) | EPHX2MAOAMAOBHDAC1HDAC2 | |
| Hydrazine SCHEMBL10768065 | 0.88 | EPHX2 (0.46) | EPHX2MAOAMAOBHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0019401-B1 | PROCESS FOR PREPARING ENAMINE DERIVATIVES, COMPOUNDS SO PRODUCED AND PROCESS FOR PREPARING A 3-HYDROXY-CEPHALOSPORIN | Lilly Industries Limited (GB) | 1984-03-21 | — | — | EP | disclosed |
| US-4301280-A | Preparation of 3-substituted cephalosporins | LILLY INDUSTRIES LIMITED (GB) | 1981-11-17 | — | — | US | disclosed |
| EP-0019401-A1 | Process for preparing enamine derivatives, compounds so produced and process for preparing a 3-hydroxy-cephalosporin | Lilly Industries Limited (GB) | 1980-11-26 | — | — | EP | disclosed |