Sugi Predict

Sugi Predict / Compounds / SCHEMBL11011306

SCHEMBL11011306

SCHEMBL11011306

CCCCNC(=O)c1ccn2c1CSC2c1cccnc1

nearest known ligand 0.60

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ PTAFR P25105 1/20 0.57
▸ TBXAS1 P24557 2/20 0.53
▸ POLB P06746 1/20 0.48
▸ MAPT P10636 1/20 0.48
▸ NPSR1 Q6W5P4 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11008637 0.90 PTAFR (0.53) PTAFRTBXAS1
SCHEMBL11013960 0.88 PTAFR (0.57) PTAFRTBXAS1
SCHEMBL10945227 0.88 PTAFR (0.55) PTAFRTBXAS1
SCHEMBL11013417 0.87 PTAFR (0.56) PTAFRTBXAS1
SCHEMBL11013295 0.87 TBXAS1 (0.66) PTAFRTBXAS1
SCHEMBL11010913 0.85 PTAFR (0.56) PTAFRTBXAS1
SCHEMBL9854052 0.85 PTAFR (0.47) PTAFRTBXAS1POLBMAPTNPSR1
SCHEMBL11013575 0.84 PTAFR (0.64) PTAFRTBXAS1
SCHEMBL11011440 0.84 PTAFR (0.64) PTAFRTBXAS1
SCHEMBL11013129 0.83 PTAFR (0.63) PTAFRTBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4529728-A 1H,3H-pyrrolo[1,2-c]thiazole derivatives having anti-allergic and anti-inflammatory activity RHONE-POULENC SANTE (FR) 1985-07-16 — — US claimed
US-4529728-A 1H,3H-pyrrolo[1,2-c]thiazole derivatives having anti-allergic and anti-inflammatory activity RHONE-POULENC SANTE (FR) 1985-07-16 — — US disclosed