Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11013166 | 1.00 | GAA (0.52) | GAAHPGDALDH1A1SMN1; SMN2POLB | |
| SCHEMBL17338653 | 0.82 | NPC1 (0.51) | HPGDALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL18807176 | 0.82 | PLAU (0.44) | HPGDALDH1A1SMN1; SMN2POLBLMNA | |
| SCHEMBL5730222 | 0.82 | NPC1 (0.51) | HPGDALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL5730216 | 0.82 | NPC1 (0.51) | HPGDALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL1018591 | 0.78 | GAA (0.65) | GAAHPGDALDH1A1SMN1; SMN2POLB | |
| SCHEMBL503977 | 0.75 | GAA (0.65) | GAAHPGDALDH1A1SMN1; SMN2POLB | |
| SCHEMBL8581819 | 0.74 | HPGD (0.62) | GAAHPGDALDH1A1SMN1; SMN2POLB | |
| SCHEMBL11004922 | 0.73 | AKR1C3 (0.48) | GAAHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11004920 | 0.73 | AKR1C3 (0.48) | GAAHPGDALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4530842-A | Containing a cyano substitution in position 3 | SANDOZ LTD. (CH) | 1985-07-23 | — | — | US | disclosed |
| WO-1983004024-A1 | 2(1H)-PYRIDONE DERIVATIVES, PREPARATION THEREOF AND COMPOSITION CONTAINING THEM | SANDOZ AG (CH) | 1983-11-24 | — | — | WO | disclosed |