Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.49 |
| ▸ | AGER | Q15109 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8579443 | 0.83 | NPC1 (0.44) | HPGDGAAKMT2AMEN1NPC1 | |
| SCHEMBL4841763 | 0.80 | NPC1 (0.57) | HPGDKMT2AMEN1NPC1RAB9A | |
| SCHEMBL503977 | 0.79 | GAA (0.65) | HPGDGAAKMT2AMEN1NPC1 | |
| SCHEMBL1018591 | 0.79 | GAA (0.65) | HPGDGAAKMT2AMEN1NPC1 | |
| SCHEMBL25343037 | 0.78 | CTSL (0.45) | HPGDGAAKMT2AMEN1NPC1 | |
| SCHEMBL6333477 | 0.78 | FLT1 (0.49) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL6496479 | 0.78 | ALDH1A1 (0.63) | HPGDGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL17319164 | 0.78 | KMT2A (0.44) | HPGDGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL4654289 | 0.78 | GAA (0.63) | HPGDGAAKMT2AMEN1NPC1 | |
| SCHEMBL8572424 | 0.75 | CYP3A4 (0.53) | KMT2AMEN1ALDH1A1MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998013341-A1 | HYDROXYBENZOPHENONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-04-02 | — | — | WO | disclosed |