Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | AGER | Q15109 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5805726 | 0.79 | LMNA (0.55) | SMN1; SMN2ALDH1A1MAPTKDM4EVCAM1 | |
| SCHEMBL2936178 | 0.75 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL12989147 | 0.75 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL2332262 | 0.75 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL11135901 | 0.75 | TSHR (0.50) | SMN1; SMN2ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL7974837 | 0.74 | LMNA (0.66) | SMN1; SMN2ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL4613713 | 0.74 | APOBEC3G (0.54) | SMN1; SMN2ALDH1A1MAPTKDM4EGAA | |
| Hydrochloric Acid SCHEMBL28541249 | 0.72 | APOBEC3G (0.52) | SMN1; SMN2ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL11014092 | 0.72 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL28109405 | 0.72 | CA12 (0.58) | SMN1; SMN2ALDH1A1MAPTGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4508723-A | 6-Azaoligocycloalkylmethyleneaminopenam compounds | CIBA GEIGY CORPORATION (US) | 1985-04-02 | — | — | US | disclosed |