Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | LAP3 | P28838 | 2/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10818937 | 0.80 | SIGMAR1 (0.36) | OPRM1POLBMAPTTDP1L3MBTL1 | |
| SCHEMBL22650301 | 0.80 | NR1I2 (0.37) | SLC2A1OPRM1LMNATDP1L3MBTL1 | |
| SCHEMBL21515786 | 0.78 | NR1I2 (0.39) | SLC2A1OPRM1LMNA | |
| SCHEMBL20222855 | 0.78 | NR1I2 (0.39) | SLC2A1OPRM1LMNA | |
| SCHEMBL21100958 | 0.78 | NR1I2 (0.39) | SLC2A1OPRM1LMNA | |
| SCHEMBL2258460 | 0.77 | SLC6A4 (0.42) | — | |
| SCHEMBL18738893 | 0.77 | NR1I2 (0.38) | SLC2A1CA2LMNA | |
| SCHEMBL21786531 | 0.76 | NR1I2 (0.37) | SLC2A1LMNA | |
| SCHEMBL22222931 | 0.76 | NR1I2 (0.47) | SLC2A1LMNA | |
| Bromide SCHEMBL9626445 | 0.74 | MAPT (0.35) | SLC2A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4551460-A | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1985-11-05 | — | — | US | disclosed |