Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HK2 | P52789 | 4/20 | 0.41 |
| ▸ | HK1 | P19367 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | PYGB | P11216 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | OGA | O60502 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.38 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.38 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.38 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15871968 | 1.00 | KDM4E (0.49) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL27436577 | 1.00 | KDM4E (0.49) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL13067603 | 1.00 | KDM4E (0.49) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL13026581 | 1.00 | KDM4E (0.49) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL31680299 | 0.85 | KDM4E (0.47) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL21059539 | 0.85 | KDM4E (0.47) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL14878932 | 0.84 | KDM4E (0.47) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL14228418 | 0.84 | GBA1 (0.33) | KDM4ELMNACYP2D6CYP2C19 | |
| SCHEMBL31001202 | 0.82 | GBA1 (0.49) | KDM4ELMNACYP2D6CYP2C19MAPK1 | |
| SCHEMBL21059535 | 0.82 | GBA1 (0.49) | KDM4ELMNACYP2D6CYP2C19MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250223392-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | ALCON INC (CH) | 2025-07-10 | — | — | US | disclosed |
| US-12286501-B2 | Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof | ALCON INC. (CH) | 2025-04-29 | — | — | US | disclosed |
| US-20250059330-A1 | SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2025-02-20 | — | — | US | disclosed |
| EP-4481478-A2 | SILICONE HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2024-12-25 | — | — | EP | disclosed |
| US-12162987-B2 | Silicone hydrogel contact lenses | ALCON INC. (CH) | 2024-12-10 | — | — | US | disclosed |
| EP-4235274-B1 | SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2024-10-09 | — | — | EP | disclosed |
| US-20240254269-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | ALCON INC. (CH) | 2024-08-01 | — | — | US | disclosed |
| US-11926689-B2 | Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof | ALCON INC. (CH) | 2024-03-12 | — | — | US | disclosed |
| US-20240018309-A1 | SILICONE HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2024-01-18 | — | — | US | disclosed |
| US-11802182-B2 | Silicone hydrogel contact lenses | ALCON INC. (CH) | 2023-10-31 | — | — | US | disclosed |
| US-20180362697-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | ALCON INC. (CH) | 2018-12-20 | — | — | US | disclosed |
| US-20180355112-A1 | SILICONE HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2018-12-13 | — | — | US | disclosed |
| EP-3390498-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | Novartis AG (CH) | 2018-10-24 | — | — | EP | disclosed |
| US-10081697-B2 | Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof | NOVARTIS AG (CH) | 2018-09-25 | — | — | US | disclosed |
| WO-2017103790-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | NOVARTIS AG (CH) | 2017-06-22 | — | — | WO | disclosed |
| US-20170166673-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | ALCON INC. (CH) | 2017-06-15 | — | — | US | disclosed |
| US-20120189571-A1 | NANOSCALE PLATINUM COMPOUNDS AND METHODS OF USE THEREOF | THE BRIGHAM AND WOMEN'S HOSPITAL., INC. (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120165495-A1 | RESORBABLE PHENOLIC POLYMERS | TYRX, INC. (US) | 2012-06-28 | — | — | US | disclosed |
| US-8153837-B2 | Resorbable phenolic polymers | TYRX, INC. (US) | 2012-04-10 | — | — | US | disclosed |
| US-20090088548-A1 | Resorbable Phenolic Polymers | TYRX PHARMA, INC. (US) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165495-A1 | RESORBABLE PHENOLIC POLYMERS | PAH, PUF60, MKI67 | KDM4E 396/4885LMNA 3812/4885CYP2D6 459/4885 |
| US-20120189571-A1 | NANOSCALE PLATINUM COMPOUNDS AND METHODS OF USE THEREOF | SGMS2, PLIN3, PHOSPHO1 | KDM4E 2871/4885LMNA 3199/4885CYP2D6 892/4885 |
| US-20090088548-A1 | Resorbable Phenolic Polymers | PAH, PUF60, MKI67 | KDM4E 396/4885LMNA 3812/4885CYP2D6 459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.