Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.46 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | PAM | P19021 | 2/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.41 |
| ▸ | AKT1 | P31749 | 2/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9404184 | 1.00 | TLR4 (0.46) | TLR4DGKATNFPAMLPAR1 | |
| SCHEMBL9404178 | 0.88 | TLR4 (0.46) | TLR4DGKAPAMLPAR1LPAR3 | |
| SCHEMBL17318241 | 0.88 | TLR4 (0.51) | TLR4DGKAPAMLPAR1LPAR3 | |
| SCHEMBL2195708 | 0.86 | TLR4 (0.53) | TLR4DGKAPAMLPAR1LPAR3 | |
| SCHEMBL2830913 | 0.86 | TLR4 (0.53) | TLR4DGKAPAMLPAR1LPAR3 | |
| SCHEMBL7049923 | 0.86 | TLR4 (0.53) | TLR4DGKAPAMLPAR1LPAR3 | |
| SCHEMBL13561244 | 0.86 | TLR4 (0.53) | TLR4DGKAPAMLPAR1LPAR3 | |
| SCHEMBL9230101 | 0.86 | TLR4 (0.53) | TLR4DGKAPAMLPAR1LPAR3 | |
| SCHEMBL9225257 | 0.86 | TLR4 (0.53) | TLR4DGKAPAMLPAR1LPAR3 | |
| SCHEMBL21662370 | 0.86 | TLR4 (0.53) | TLR4DGKAPAMLPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0144894-A2 | Therapeutic application of substituted O-acyl-glycosides | BAYER AG (DE) | 1985-06-19 | — | — | EP | claimed |
| EP-0144894-A2 | Therapeutic application of substituted O-acyl-glycosides | BAYER AG (DE) | 1985-06-19 | — | — | EP | disclosed |