SCHEMBL2195708

SCHEMBL2195708

CCCCCCCCCCCCCCCCCC(=O)OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 1/20 0.53
SLC2A1 P11166 1/20 0.49
DGKA P23743 1/20 0.49
AKT1 P31749 2/20 0.46
PAM P19021 2/20 0.45
VEGFA P15692 3/20 0.45
SELP P16109 1/20 0.45
PTGS1 P23219 1/20 0.44
PTGS2 P35354 1/20 0.44
LPAR1 Q92633 2/20 0.44
LPAR3 Q9UBY5 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2195712 1.00 TLR4 (0.53) TLR4SLC2A1DGKAAKT1PAM
SCHEMBL7049923 1.00 TLR4 (0.53) TLR4SLC2A1DGKAAKT1PAM
SCHEMBL2200385 1.00 TLR4 (0.53) TLR4SLC2A1DGKAAKT1PAM
SCHEMBL13561244 1.00 TLR4 (0.53) TLR4SLC2A1DGKAAKT1PAM
SCHEMBL21662370 1.00 TLR4 (0.53) TLR4SLC2A1DGKAAKT1PAM
SCHEMBL9225257 1.00 TLR4 (0.53) TLR4SLC2A1DGKAAKT1PAM
SCHEMBL2830913 1.00 TLR4 (0.53) TLR4SLC2A1DGKAAKT1PAM
SCHEMBL9230101 1.00 TLR4 (0.53) TLR4SLC2A1DGKAAKT1PAM
SCHEMBL13561243 1.00 TLR4 (0.53) TLR4SLC2A1DGKAAKT1PAM
SCHEMBL9390433 1.00 TLR4 (0.53) TLR4SLC2A1DGKAAKT1PAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2861205-B1 COMPOSITION INCLUDING A PYRIDINE DICARBOXYLIC ACID ESTER AND A GLUCOSE AND FATTY ACID ESTER. OREAL (FR) 2017-12-06 EP claimed
CN-104363887-A Compositions, methods and uses comprising pyridine dicarboxylic acid esters and esters of glucose and fatty acids OREAL 2015-02-18 CN claimed
US-8729254-B2 Derivative of glucose and vitamin F, compositions comprising it, uses and preparation process L'OREAL (FR) 2014-05-20 US claimed
EP-1837341-B1 Derivative of glucose and vitamin F, compositions containing it, its uses to improve the state of hair OREAL (FR) 2011-08-03 EP claimed
US-7763587-B2 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process L'OREAL S.A. (FR) 2010-07-27 US claimed
US-20100143279-A1 COSMETIC/DERMATOLOGICAL COMPOSITIONS COMPRISING A DERIVATIVE OF GLUCOSE AND OF VITAMIN F AND A SPECIFIC SURFACTANT L'OREAL (FR) 2010-06-10 US claimed
US-20090149396-A1 DERIVATIVE OF GLUCOSE AND VITAMIN F, COMPOSITIONS COMPRISING IT, USES AND PREPARATION PROCESS L'OREAL S.A. 2009-06-11 US claimed
CN-100469348-C Cosmetic/dermatological compositions OREAL (FR) 2009-03-18 CN claimed
EP-1837341-A1 Derivative of glucose and vitamin F, compositions containing it, its uses and its preparation L'Oréal (FR) 2007-09-26 EP claimed
EP-1371658-B1 Derivative of glucose and vitamin F, compositions containing it, its uses and its preparation OREAL (FR) 2007-09-12 EP claimed
US-20060165630-A1 Use of amide or ester of sugar and of fatty acid, for treating and/or preventing dry skin L'OREAL (FR) 2006-07-27 US claimed
US-20060106209-A1 Novel process for the preparation of o-acylated glucose derivatives L'OREAL (FR) 2006-05-18 US claimed
EP-1551362-A2 USE OF AMIDE OR ESTER OF SUGAR AND OF FATTY ACID, FOR TREATING AND/OR PREVENTING DRY SKIN. L'OREAL (FR) 2005-07-13 EP claimed
US-20040192906-A1 Novel process for the preparation of O-acylated glucose derivatives L'OREAL (FR) 2004-09-30 US claimed
EP-1454913-A1 Method for the synthesis of O-acylated derivatives of glucose L'OREAL (FR) 2004-09-08 EP claimed
WO-2004034958-A2 USE OF AMIDE OR ESTER OF SUGAR AND OF FATTY ACID, FOR TREATING AND/OR PREVENTING DRY SKIN L'OREAL (FR) 2004-04-29 WO claimed
US-20040038912-A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process L'OREAL S.A. (FR) 2004-02-26 US claimed
EP-1371658-A1 Derivative of glucose and vitamin F, compositions containing it, its uses and its preparation L'OREAL (FR) 2003-12-17 EP claimed
EP-0394280-B1 ESTERS OF GLYCOSIDES AND A PROCESS FOR ENZYMATIC PREPARATION THEREOF NOVO NORDISK AS (DK) 1995-04-05 EP claimed
WO-1991012305-A1 OIL REMOVAL NOVO NORDISK A/S (DK) 1991-08-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060106209-A1 Novel process for the preparation of o-acylated glucose derivatives SLC2A4, SLC2A3, SLC5A2 TLR4 2746/4885SLC2A1 4/4885DGKA 672/4885
US-20100143279-A1 COSMETIC/DERMATOLOGICAL COMPOSITIONS COMPRISING A DERIVATIVE OF GLUCOSE AND OF VITAMIN F AND A SPECIFIC SURFACTANT HKDC1, ADH1B, HK1 TLR4 3459/4885SLC2A1 151/4885DGKA 751/4885
US-20040192906-A1 Novel process for the preparation of O-acylated glucose derivatives SLC2A4, SLC2A3, SLC5A2 TLR4 2746/4885SLC2A1 4/4885DGKA 672/4885
US-20090149396-A1 DERIVATIVE OF GLUCOSE AND VITAMIN F, COMPOSITIONS COMPRISING IT, USES AND PREPARATION PROCESS FASN, ELOVL6, FADS2 TLR4 2700/4885SLC2A1 75/4885DGKA 552/4885
US-20040038912-A1 Derivative of glucose and of vitamin F, compositions comprising it, uses and preparation process FASN, ELOVL6, ACSL6 TLR4 2674/4885SLC2A1 86/4885DGKA 584/4885
US-20060165630-A1 Use of amide or ester of sugar and of fatty acid, for treating and/or preventing dry skin CUTA, SCD5, SCD TLR4 685/4885SLC2A1 243/4885DGKA 504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.