Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.39 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.39 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.39 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.39 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.39 |
| ▸ | ATP1B3 | P54709 | 2/20 | 0.39 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.39 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.34 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2995208 | 0.96 | CYP19A1 (0.39) | CYP19A1ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL29222975 | 0.77 | HSD11B1 (0.33) | CYP19A1HSD11B1 | |
| SCHEMBL2990884 | 0.76 | CYP19A1 (0.39) | CYP19A1ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL5409872 | 0.73 | HSD17B10 (0.40) | HSD17B10 | |
| SCHEMBL6537000 | 0.73 | CYP19A1 (0.38) | CYP19A1ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL27732284 | 0.73 | CYP19A1 (0.38) | CYP19A1ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL11349571 | 0.73 | CYP19A1 (0.38) | CYP19A1ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL16029934 | 0.73 | CYP19A1 (0.38) | CYP19A1ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL669797 | 0.73 | CYP19A1 (0.38) | CYP19A1ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL3000617 | 0.72 | HSD17B10 (0.37) | HSD17B10GPBAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0131837-A1 | Liquid crystalline compounds | MERCK PATENT GmbH (DE) | 1985-01-23 | — | — | EP | disclosed |