SCHEMBL11014378

SCHEMBL11014378

O=[N+]([O-])c1ccc2nn(-c3cc(O)ccc3O)cc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.49
KMT2A Q03164 5/20 0.49
RAB9A P51151 4/20 0.49
MAPT P10636 4/20 0.49
NPC1 O15118 3/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
LMNA P02545 2/20 0.49
NFKB1 P19838 1/20 0.47
CASP3 P42574 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
ESR2 Q92731 1/20 0.45
SNCA P37840 1/20 0.45
GUCY1B2 O75343 1/20 0.43
GUCY1A2 P33402 1/20 0.43
GUCY1A1 Q02108 1/20 0.43
GUCY1B1 Q02153 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11012636 0.91 MEN1 (0.60) MEN1KMT2ARAB9AMAPTNPC1
SCHEMBL11010720 0.89 MEN1 (0.53) MEN1KMT2ARAB9AMAPTNPC1
SCHEMBL11013407 0.82 MEN1 (0.47) MEN1KMT2ARAB9AMAPTNPC1
SCHEMBL8762676 0.81 MEN1 (0.50) MEN1KMT2ARAB9AMAPTNPC1
SCHEMBL11016239 0.80 MEN1 (0.46) MEN1KMT2ARAB9AMAPTNPC1
SCHEMBL11012992 0.80 MEN1 (0.51) MEN1KMT2ARAB9AMAPTNPC1
SCHEMBL11011315 0.79 MEN1 (0.47) MEN1KMT2ARAB9AMAPTNPC1
SCHEMBL11008465 0.78 RAB9A (0.51) MEN1KMT2ARAB9AMAPTNPC1
SCHEMBL11009441 0.77 ESR2 (0.50) MEN1KMT2AMAPTESR2ERN1
SCHEMBL11010166 0.77 ESR2 (0.50) MEN1KMT2ARAB9AMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4501898-A Photographic development inhibitor (1H- or 2H-) indazolyl hydroquinone derivatives FUJI PHOTO FILM CO., LTD. (JP) 1985-02-26 US disclosed
US-4345024-A A 3-INDAZOL-1 OR 2-YL HYDROQUINONE DERIVATIVE IN A PHOTOSENSITIVE SILVER HALIDE EMULSION; COLOR FILMS; BLACK AND WHITE PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 1982-08-17 US disclosed