SCHEMBL110147

SCHEMBL110147

CCCCCCCCCCCCOC(=O)C(N)CCSC

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NOD1 Q9Y239 4/20 0.49
NAAA Q02083 1/20 0.44
EPHX1 P07099 1/20 0.42
MARS1 P56192 5/20 0.41
TSHR P16473 2/20 0.41
HTR2C P28335 1/20 0.41
HCAR2 Q8TDS4 1/20 0.39
RAD52 P43351 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL113748 1.00 NOD1 (0.49) NOD1NAAAEPHX1MARS1TSHR
SCHEMBL8852410 1.00 NOD1 (0.49) NOD1NAAAEPHX1MARS1TSHR
SCHEMBL8852558 1.00 NOD1 (0.49) NOD1NAAAEPHX1MARS1TSHR
SCHEMBL111280 1.00 NOD1 (0.49) NOD1NAAAEPHX1MARS1TSHR
SCHEMBL7780237 1.00 NOD1 (0.49) NOD1NAAAEPHX1MARS1TSHR
SCHEMBL112341 1.00 NOD1 (0.49) NOD1NAAAEPHX1MARS1TSHR
SCHEMBL2928691 1.00 NOD1 (0.49) NOD1NAAAEPHX1MARS1TSHR
SCHEMBL110148 1.00 NOD1 (0.49) NOD1NAAAEPHX1MARS1TSHR
SCHEMBL8852439 1.00 NOD1 (0.49) NOD1NAAAEPHX1MARS1TSHR
SCHEMBL2928692 1.00 NOD1 (0.49) NOD1NAAAEPHX1MARS1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102802605-A Stable lipid formulations of apoptosis promoters ABBOTT LAB 2012-11-28 CN claimed
EP-2424499-A1 STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER Abbott Laboratories (US) 2012-03-07 EP claimed
US-20100278905-A1 STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER ABBVIE INC. 2010-11-04 US claimed
WO-2010127193-A1 STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER ABBOTT LABORATORIES (US) 2010-11-04 WO claimed
US-6372788-B1 None US disclosed
CN-117843540-A Methionine derivative, preparation method thereof and application of gene vector 黑龙江八一农垦大学 2024-04-09 CN disclosed
CN-117843541-A Lipid compound containing sulfonium cations, preparation method thereof and application of gene vector 黑龙江八一农垦大学 2024-04-09 CN disclosed
CN-102655858-B ABT-263 capsule ABBVIE (US) 2015-11-25 CN disclosed
CN-102802605-B Stable lipid formulations of apoptosis promoters ABBVIE (US) 2015-08-12 CN disclosed
US-8927009-B2 ABT-263 capsule ABBVIE INC. (US) 2015-01-06 US disclosed
US-8728516-B2 Stabilized lipid formulation of apoptosis promoter ABBVIE INC. (US) 2014-05-20 US disclosed
US-8513243-B2 ABT-263 crystalline forms ABBVIE INC. (US) 2013-08-20 US disclosed
CN-1326322-A Method for supplying bioavailable methionine to cow AVENTIS ANIMAL NUTRITION SA (FR) 2001-12-12 CN disclosed
EP-1135398-A1 CYANOPHOSPHONAMIDES AND METHOD FOR PREPARATION Monsanto Technology LLC (US) 2001-09-26 EP disclosed
EP-1128738-A1 A METHOD FOR SUPPLYING BIOAVAILABLE METHIONINE TO A COW AVENTIS ANIMAL NUTRITION S.A. (FR) 2001-09-05 EP disclosed
US-20010008904-A1 Method for supplying bioavailable methionine to a cow RHONE-POULENC ANIMAL NUTRITION 2001-07-19 US disclosed
US-6221909-B1 ADMINISTERING TO THE COW THE ISOPROPYL ESTER OF THE HYDROXY ANALOGUE OF METHIONINE. RHôNE-POULENC ANIMAL NUTRITION (FR) 2001-04-24 US disclosed
US-6218563-B1 Cyanophosphonamides and method for preparation MONSANTO COMPANY 2001-04-17 US disclosed
WO-2000032611-A1 CYANOPHOSPHONAMIDES AND METHOD FOR PREPARATION MONSANTO TECHNOLOGY LLC (US) 2000-06-08 WO disclosed
WO-2000028835-A1 A METHOD FOR SUPPLYING BIOAVAILABLE METHIONINE TO A COW AVENTIS ANIMAL NUTRITION S.A. (FR) 2000-05-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100278905-A1 STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER BCL2, BAX, BCOR NOD1 2795/4885NAAA 4513/4885EPHX1 4584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.