⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10363981 | 0.86 | — | — | |
| SCHEMBL27416007 | 0.60 | — | — | |
| SCHEMBL11010375 | 0.60 | KDM4E (0.32) | — | |
| 2-(Nitromethylene)Thiazolidine SCHEMBL1871573 | 0.58 | — | — | |
| 2-(Nitromethylene)Thiazolidine SCHEMBL10363912 | 0.58 | — | — | |
| 2-(Nitromethylene)Thiazolidine SCHEMBL1871570 | 0.58 | — | — | |
| SCHEMBL7514475 | 0.53 | — | — | |
| 2-(Nitromethylene)Imidazolidine SCHEMBL2069003 | 0.52 | — | — | |
| SCHEMBL265642 | 0.52 | — | — | |
| SCHEMBL21409043 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105601584-A | Thiazolidine derivatives, and preparation method and applications thereof | TIANJIN HANKANG PHARMACEUTICAL BIOTECHNOLOGY CO LTD | 2016-05-25 | — | — | CN | disclosed |
| CN-105601583-A | Thiazolidine derivatives, and preparation method and applications thereof | TIANJIN HANKANG PHARMACEUTICAL BIOTECHNOLOGY CO LTD | 2016-05-25 | — | — | CN | disclosed |
| EP-0135803-A2 | Process for producing heterocyclic compounds having nitromethylene group as the side chain group | UBE INDUSTRIES, LTD. (JP) | 1985-04-03 | — | — | EP | disclosed |
| EP-0115323-A2 | Process for producing heterocyclic compound having nitromethylene group as the side chain group | UBE INDUSTRIES, LTD. (JP) | 1984-08-08 | — | — | EP | disclosed |