SCHEMBL7514475

SCHEMBL7514475

O=[N+]([O-])C=C1SCCS1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7518953 0.90 ALDH1A1 (0.33)
2-(Nitromethylene)Thiazolidine SCHEMBL1871570 0.67
2-(Nitromethylene)Thiazolidine SCHEMBL1871573 0.67
SCHEMBL7558075 0.67 MEN1 (0.33)
SCHEMBL7558072 0.67 MEN1 (0.33)
2-(Nitromethylene)Thiazolidine SCHEMBL10363912 0.67
SCHEMBL10364031 0.66 INMT (0.40)
SCHEMBL11709202 0.66 INMT (0.40)
SCHEMBL15868363 0.65
SCHEMBL5878423 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0765870-B1 Broad-spectrum antimicrobially active compounds ROHM & HAAS (US) 2002-02-13 EP disclosed
US-6297374-B1 Nitroimino-nitromethylene—azole or-azine heterocyclic compounds, insecticidal compositions containing them, and insecticidal methods of using them NIHON BAYER AGROCHEM K.K. (JP) 2001-10-02 US disclosed
US-6022967-A 1-NITRO-2-CARBOXYVINYL- OR 1-NITRO-2-(DIMETHYLAMINO)VINYL-SUBSTITUTED IMIDAZOLIDINES OR TETRAHYDROPYRIMIDINES NIHON BAYER AGROCHEM K.K. (JP) 2000-02-08 US disclosed
US-5883134-A APPLYING 1-(ALKYLSULFINYL- OR ALKYLSULFONYL)-2-NITROETHENE DERIVATIVE AS BACTERICIDE, FUNGICIDE, AND/OR ALGICIDE ROHM AND HAAS COMPANY (US) 1999-03-16 US disclosed
US-5750704-A INSECTICIDES NIHON BAYER AGROCHEM K.K. (JP) 1998-05-12 US disclosed
CN-1160481-A Broad-spectrum antimicrobially active compounds ROHM & HAAS (US) 1997-10-01 CN disclosed
EP-0765870-A2 Broad-spectrum antimicrobially active compounds ROHM AND HAAS COMPANY (US) 1997-04-02 EP disclosed
US-5580889-A Insecticidal nitromethyl or niteoimino-heteromethyl-heterocyclics NIHON BAYER AGROCHEM K.K. (JP) 1996-12-03 US disclosed
US-5461167-A 2-chloro-5-chloromethyl thiazole; insecticide NIHON BAYER AGROCHEM K.K. (JP) 1995-10-24 US disclosed
US-5428032-A Insecticides NIHON BAYER AGROCHEM K.K. (JP) 1995-06-27 US disclosed
US-4742060-A 2-(NITROIMINO)- OR 2-(NITROMETHYLENE)-IMIDAZOLIDINES AS INSECTICIDES NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) 1988-05-03 US disclosed
EP-0154178-B1 NITROMETHYLENE DERIVATIVES, METHOD FOR THEIR PREPARATION AND INSECTICIDAL, MITICIDAL AND NEMATICIDAL AGENTS NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1987-10-07 EP disclosed
US-4680294-A Pesticidal novel nitromethylene derivatives NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1987-07-14 US disclosed
US-4678795-A 1-pyridylmethyl-2-nitromethylene-1,3-diazacycloalkane insecticides NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1987-07-07 US disclosed
EP-0212600-A2 Nitromethylene derivatives NIHON BAYER AGROCHEM K.K. (JP) 1987-03-04 EP disclosed
US-4647570-A Pesticidal novel nitromethylene derivatives NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1987-03-03 US disclosed
EP-0199974-A2 Nitromethylene-tetrahydropyrimidine NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1986-11-05 EP disclosed
EP-0192060-A1 Heterocyclic compounds NIHON BAYER AGROCHEM K.K. (JP) 1986-08-27 EP disclosed
EP-0163855-A1 Nitromethylene derivatives, intermediates, and process for their preparation as insecticides NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1985-12-11 EP disclosed
EP-0154178-A1 Nitromethylene derivatives, method for their preparation and insecticidal, miticidal and nematicidal agents NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1985-09-11 EP disclosed