Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAT2A | P31153 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3774502 | 0.84 | LMNA (0.48) | KDM4EKMT2AGAAMAPTLMNA | |
| SCHEMBL3486575 | 0.81 | KDM4E (0.71) | KDM4EKMT2AGAAMAPTLMNA | |
| SCHEMBL6502520 | 0.81 | KMT2A (0.49) | KDM4EKMT2AMEN1GAAMAPT | |
| SCHEMBL29516815 | 0.81 | KMT2A (0.49) | KDM4EKMT2AMEN1GAAMAPT | |
| SCHEMBL11014507 | 0.79 | KMT2A (0.74) | KMT2AMEN1GAAMAPTALDH1A1 | |
| SCHEMBL10987025 | 0.78 | KMT2A (0.52) | KDM4EKMT2AMEN1GAAMAPT | |
| SCHEMBL6693265 | 0.78 | KMT2A (0.73) | KDM4EKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL13585193 | 0.77 | SMN1; SMN2 (0.73) | KDM4EKMT2AMEN1GAAMAPT | |
| SCHEMBL28641620 | 0.77 | AR (0.45) | KDM4EKMT2AMEN1GAAMAPT | |
| SCHEMBL6693258 | 0.76 | GAA (0.55) | KDM4EKMT2AMEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4540696-A | 1-Piperazinyl 4-phenylquinazoline compounds having antidepressant properties and drugs containing same | SANOFI S.A. (FR) | 1985-09-10 | — | — | US | disclosed |