Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 6/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14938984 | 0.86 | ALDH1A1 (0.52) | KMT2AALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL11015414 | 0.80 | MAOB (0.50) | KMT2AALDH1A1HPGDMEN1SMN1; SMN2 | |
| SCHEMBL11119313 | 0.78 | HPGD (0.56) | KMT2AKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL7273984 | 0.75 | KMT2A (0.46) | KMT2APOLBCYP1A2CYP2C19MEN1 | |
| SCHEMBL2152981 | 0.74 | MAPT (0.43) | KMT2AALDH1A1POLBCYP2C9CYP2C19 | |
| SCHEMBL11013892 | 0.74 | CNR1 (0.41) | KMT2AALDH1A1HPGDMEN1MAPT | |
| SCHEMBL14938844 | 0.73 | POLB (0.54) | KMT2AKDM4EALDH1A1HPGDPOLB | |
| SCHEMBL7270797 | 0.72 | PPARG (0.43) | KMT2APOLBMEN1MAPTGAA | |
| SCHEMBL7273629 | 0.72 | MAPK7 (0.42) | KMT2AHPGDCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7264544 | 0.72 | EPHX2 (0.45) | KMT2AALDH1A1HPGDPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151528-A2 | 5-(Amino or substituted amino)-1,2,3-triazoles | MERCK & CO. INC. (US) | 1985-08-14 | — | — | EP | disclosed |