Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.55 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11015286 | 1.00 | HTT (0.68) | HTTSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL11015276 | 1.00 | HTT (0.68) | HTTSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL11010956 | 0.84 | HTT (0.68) | HTTSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL11010949 | 0.84 | HTT (0.68) | HTTSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL10199018 | 0.83 | ALDH1A1 (0.76) | HTTSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL10936745 | 0.83 | ALDH1A1 (0.76) | HTTSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL11140025 | 0.81 | KDM4E (0.81) | HTTSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL11140030 | 0.81 | KDM4E (0.81) | HTTSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL12172767 | 0.81 | ALDH1A1 (1.00) | HTTSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL11013191 | 0.78 | ALDH1A1 (0.65) | HTTSMN1; SMN2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4500719-A | Process for the preparation of N-alkenylphenylmaleimides and N,N'-[alkenylenephenylene]bismalemides | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1985-02-19 | — | — | US | disclosed |
| US-4376206-A | QUICK-CURABLE HEAT RESISTANT RESINS | MITSUI TOATSU CHEMICALS, INC. (JP) | 1983-03-08 | — | — | US | disclosed |