Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8158074 | 0.85 | SMN1; SMN2 (0.34) | TDP1CYP3A4HDAC3HDAC4HDAC1 | |
| SCHEMBL8159899 | 0.83 | SMN1; SMN2 (0.33) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8159898 | 0.83 | PABPC1 (0.41) | CA2TDP1CYP3A4 | |
| SCHEMBL29179 | 0.82 | CYP3A4 (0.45) | TDP1CYP3A4 | |
| Carbon Monoxide SCHEMBL11109139 | 0.80 | APP (0.31) | — | |
| SCHEMBL7164452 | 0.80 | TDP1 (0.43) | TDP1CYP3A4 | |
| Hydrochloric Acid SCHEMBL9322645 | 0.80 | CYP3A4 (0.43) | TDP1CYP3A4 | |
| SCHEMBL689027 | 0.80 | TDP1 (0.43) | TDP1CYP3A4 | |
| SCHEMBL3930010 | 0.80 | CYP3A4 (0.43) | TDP1CYP3A4 | |
| SCHEMBL2920316 | 0.80 | CYP3A4 (0.43) | TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0133127-A1 | Sulphonated chiral phosphines, their preparation and their use in asymmetric catalysis | RHONE-POULENC SANTE (FR) | 1985-02-13 | — | — | EP | disclosed |