SCHEMBL11015481

SCHEMBL11015481

CCCCCCCCCCCCN(C)C(=O)NN

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 7/20 0.47
DNM1 Q05193 6/20 0.43
KDM5A P29375 3/20 0.40
KDM4C Q9H3R0 2/20 0.40
PHF8 Q9UPP1 1/20 0.40
S1PR2 O95136 1/20 0.39
S1PR1 P21453 1/20 0.39
S1PR3 Q99500 1/20 0.39
S1PR5 Q9H228 1/20 0.39
EPHX1 P07099 2/20 0.38
KDM5C P41229 1/20 0.38
KDM5B Q9UGL1 1/20 0.38
GGPS1 O95749 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11019738 0.92 CA1 (0.39) EPHX2DNM1KDM5AKDM4CPHF8
SCHEMBL8045017 0.81 DNM1 (0.48) EPHX2DNM1S1PR2S1PR1S1PR3
SCHEMBL77146 0.81 DNM1 (0.48) EPHX2DNM1S1PR2S1PR1S1PR3
SCHEMBL28026183 0.81 DNM1 (0.48) EPHX2DNM1S1PR2S1PR1S1PR3
SCHEMBL25229293 0.81 DNM1 (0.48) EPHX2DNM1S1PR2S1PR1S1PR3
SCHEMBL25271927 0.81 DNM1 (0.48) EPHX2DNM1S1PR2S1PR1S1PR3
SCHEMBL30312246 0.81 DNM1 (0.48) EPHX2DNM1S1PR2S1PR1S1PR3
SCHEMBL11681451 0.81 DNM1 (0.48) EPHX2DNM1S1PR2S1PR1S1PR3
SCHEMBL291725 0.81 DNM1 (0.48) EPHX2DNM1S1PR2S1PR1S1PR3
SCHEMBL7994525 0.81 DNM1 (0.48) EPHX2DNM1S1PR2S1PR1S1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0146027-A2 Selected n,1-disubstituted hydrazine-carboxamides and their use as antioxidants OLIN CORPORATION (US) 1985-06-26 EP claimed