Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11008227 | 0.90 | ALDH1A1 (0.75) | MAPK1TP53ALDH1A1HSD17B10KDM4E | |
| SCHEMBL11012408 | 0.90 | ALDH1A1 (0.78) | MAPK1TP53ALDH1A1HSD17B10KDM4E | |
| SCHEMBL11011102 | 0.88 | ALDH1A1 (0.75) | MAPK1TP53ALDH1A1HSD17B10KDM4E | |
| SCHEMBL11009202 | 0.88 | ALDH1A1 (0.75) | MAPK1TP53ALDH1A1HSD17B10KDM4E | |
| SCHEMBL11010526 | 0.88 | ALDH1A1 (0.78) | MAPK1TP53ALDH1A1HSD17B10KDM4E | |
| SCHEMBL11011425 | 0.88 | ALDH1A1 (0.81) | MAPK1TP53ALDH1A1HSD17B10KDM4E | |
| SCHEMBL11011511 | 0.88 | ALDH1A1 (0.75) | MAPK1TP53ALDH1A1HSD17B10KDM4E | |
| SCHEMBL11012294 | 0.87 | ALDH1A1 (0.72) | MAPK1TP53ALDH1A1HSD17B10KDM4E | |
| SCHEMBL11012654 | 0.87 | ALDH1A1 (0.72) | MAPK1TP53ALDH1A1HSD17B10KDM4E | |
| SCHEMBL11008738 | 0.87 | ALDH1A1 (0.72) | MAPK1TP53ALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4507315-A | Hypoglycaemic and hypolipidaemic benzamide substituted (1H-) imidazole derivatives and compositions | MAY & BAKER LIMITED (GB) | 1985-03-26 | — | — | US | disclosed |