Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11015965 | 1.00 | TSHR (0.43) | TSHRALDH1A1LMNAMAPTCYP3A4 | |
| SCHEMBL9395434 | 0.86 | TSHR (0.48) | TSHRALDH1A1MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL9395446 | 0.86 | TSHR (0.48) | TSHRALDH1A1MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL11060418 | 0.84 | NR1I2 (0.47) | TSHRALDH1A1LMNAMAPTCYP3A4 | |
| SCHEMBL28499337 | 0.84 | NR1I2 (0.47) | TSHRALDH1A1LMNAMAPTCYP3A4 | |
| SCHEMBL11060420 | 0.84 | NR1I2 (0.47) | TSHRALDH1A1LMNAMAPTCYP3A4 | |
| SCHEMBL28263077 | 0.81 | TSHR (0.51) | TSHRALDH1A1LMNAMAPTCYP3A4 | |
| SCHEMBL11220169 | 0.81 | MGLL (0.41) | TSHRALDH1A1LMNAMAPTCYP3A4 | |
| SCHEMBL11220172 | 0.81 | MGLL (0.41) | TSHRALDH1A1LMNAMAPTCYP3A4 | |
| SCHEMBL15624121 | 0.80 | TSHR (0.54) | TSHRALDH1A1LMNAMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4416823-A | Dimeric carbonylation of 1,3-alkadiene | CELANESE CORPORATION (US) | 1983-11-22 | — | — | US | claimed |
| US-4269781-A | Dimeric carbonylation of 1,3-butadiene | CELANESE CORPORATION (US) | 1981-05-26 | — | — | US | claimed |
| US-4584144-A | Monomeric thioloesterification of 1,3-alkadiene | CELANESE CORPORATION (US) | 1986-04-22 | — | — | US | disclosed |
| US-4471067-A | Dimeric carbonylation of 1,3-alkadiene | CELANESE CORPORATION (US) | 1984-09-11 | — | — | US | disclosed |
| US-4416823-A | Dimeric carbonylation of 1,3-alkadiene | CELANESE CORPORATION (US) | 1983-11-22 | — | — | US | disclosed |
| US-4269781-A | Dimeric carbonylation of 1,3-butadiene | CELANESE CORPORATION (US) | 1981-05-26 | — | — | US | disclosed |