Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 7/20 | 0.72 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.72 |
| ▸ | PGR | P06401 | 6/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.68 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.68 |
| ▸ | AR | P10275 | 2/20 | 0.68 |
| ▸ | TNF | P01375 | 1/20 | 0.68 |
| ▸ | IL6 | P05231 | 1/20 | 0.68 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.68 |
| ▸ | GLUL | P15104 | 1/20 | 0.68 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.68 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6857090 | 1.00 | NR3C2 (0.72) | NR3C2NR3C1PGRHIF1AHSD17B10 | |
| SCHEMBL6857093 | 1.00 | NR3C2 (0.72) | NR3C2NR3C1PGRHIF1AHSD17B10 | |
| Prednival SCHEMBL11585728 | 0.96 | HIF1A (0.73) | NR3C2NR3C1PGRHIF1AHSD17B10 | |
| Prednival SCHEMBL25387 | 0.96 | HIF1A (0.73) | NR3C2NR3C1PGRHIF1AHSD17B10 | |
| Prednival SCHEMBL25388 | 0.96 | HIF1A (0.73) | NR3C2NR3C1PGRHIF1AHSD17B10 | |
| Prednival SCHEMBL2966212 | 0.96 | HIF1A (0.73) | NR3C2NR3C1PGRHIF1AHSD17B10 | |
| Prednival SCHEMBL2966209 | 0.96 | HIF1A (0.73) | NR3C2NR3C1PGRHIF1AHSD17B10 | |
| SCHEMBL7984 | 0.94 | NR3C2 (0.74) | NR3C2NR3C1PGRHIF1AHSD17B10 | |
| SCHEMBL7142733 | 0.94 | NR3C2 (0.74) | NR3C2NR3C1PGRHIF1AHSD17B10 | |
| SCHEMBL7613014 | 0.94 | NR3C2 (0.74) | NR3C2NR3C1PGRHIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116348093-A | Pharmaceutical composition of intra-articular corticosteroid for pain control | TLC生物医药公司 | 2023-06-27 | — | — | CN | claimed |
| CN-112702993-A | Pharmaceutical compositions suitable for joint delivery and their use in the treatment of joint pain | TLC生物医药公司 | 2021-04-23 | — | — | CN | claimed |
| CN-112469420-A | Method for reducing complications of steroids in joints | 台湾微脂体股份有限公司 | 2021-03-09 | — | — | CN | claimed |
| US-4478818-A | Ocular preparation housing steroid in two different therapeutic forms | ALZA CORPORATION (US) | 1984-10-23 | — | — | US | claimed |
| CN-119490468-A | Solid forms of acanthogenesis promoting agent | 斯皮诺吉尼克斯公司 | 2025-02-21 | — | — | CN | disclosed |
| CN-119235874-A | Combination therapy for prostate cancer | 詹森药业有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-116024266-A | Compositions and methods for treating leber's hereditary optic neuropathy due to ND4 mutations | 武汉纽福斯生物科技有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-217612538-U | Brachytherapy applicator device | 萨鲁塔利斯医疗设备有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-114901295-A | Chimeric antigen receptor T cell therapy | 凯德药业股份有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-114698370-A | Compounds and methods for treating cytokine release syndrome | 里格尔药品股份有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-114466658-A | Orally delivered therapeutic compositions and uses thereof | 沈海发 | 2022-05-10 | — | — | CN | disclosed |
| CN-114286679-A | Methods of blocking or ameliorating cytokine release syndrome | 里格尔药品股份有限公司 | 2022-04-05 | — | — | CN | disclosed |
| CN-108697713-B | Methods for making tricyclic PI3K inhibitor compounds and methods of treating cancer therewith | 基因泰克公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-112584874-A | Compositions and methods for treating leber's hereditary optic neuropathy | 武汉纽福斯生物科技有限公司 | 2021-03-30 | — | — | CN | disclosed |
| CN-107530339-B | Glucocorticoid receptor antagonists in combination with glucocorticoids for the treatment of adrenal insufficiency | 科赛普特治疗学股份有限公司 | 2021-03-16 | — | — | CN | disclosed |
| CN-110753545-A | Combination therapy for prostate cancer | 詹森药业有限公司 | 2020-02-04 | — | — | CN | disclosed |
| EP-0144086-A2 | Hydrocortisone and prednisolone derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-06-12 | — | — | EP | disclosed |
| US-4478818-A | Ocular preparation housing steroid in two different therapeutic forms | ALZA CORPORATION (US) | 1984-10-23 | — | — | US | disclosed |
| US-4432964-A | Topical composition containing steroid in two forms released independently from polymeric carrier | ALZA CORPORATION (US) | 1984-02-21 | — | — | US | disclosed |
| US-4304765-A | Ocular insert housing steroid in two different therapeutic forms | ALZA CORPORATION (US) | 1981-12-08 | — | — | US | disclosed |