Prednival

Prednival

SCHEMBL25387

CCCCC(=O)O[C@]1(C(=O)CO)CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 6/20 0.73
KMT2A Q03164 1/20 0.73
NR3C2 P08235 7/20 0.71
NR3C1 P04150 6/20 0.67
PGR P06401 6/20 0.67
HSD17B10 Q99714 3/20 0.67
CYP3A4 P08684 3/20 0.67
ABCB11 O95342 3/20 0.67
AR P10275 2/20 0.67
TNF P01375 1/20 0.67
IL6 P05231 1/20 0.67
SERPINA6 P08185 1/20 0.67
GLUL P15104 1/20 0.67
ADAM17 P78536 1/20 0.67
GPBAR1 Q8TDU6 1/20 0.67
CYP2C19 P33261 1/20 0.67
LMNA P02545 3/20 0.67
CYP2C9 P11712 2/20 0.67
USP2 O75604 1/20 0.67
CYP2D6 P10635 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Prednival SCHEMBL25388 1.00 HIF1A (0.73) HIF1AKMT2ANR3C2NR3C1PGR
Prednival SCHEMBL2966209 1.00 HIF1A (0.73) HIF1AKMT2ANR3C2NR3C1PGR
Prednival SCHEMBL11585728 1.00 HIF1A (0.73) HIF1AKMT2ANR3C2NR3C1PGR
Prednival SCHEMBL2966212 1.00 HIF1A (0.73) HIF1AKMT2ANR3C2NR3C1PGR
SCHEMBL7984 0.98 NR3C2 (0.74) HIF1AKMT2ANR3C2NR3C1PGR
SCHEMBL7142733 0.98 NR3C2 (0.74) HIF1AKMT2ANR3C2NR3C1PGR
SCHEMBL7613014 0.98 NR3C2 (0.74) HIF1AKMT2ANR3C2NR3C1PGR
SCHEMBL7145314 0.98 NR3C2 (0.74) HIF1AKMT2ANR3C2NR3C1PGR
SCHEMBL11016342 0.96 NR3C2 (0.72) HIF1AKMT2ANR3C2NR3C1PGR
SCHEMBL6857090 0.96 NR3C2 (0.72) HIF1AKMT2ANR3C2NR3C1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4980 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120154586-A Powder aerosol composition for inhalation, powder aerosol for inhalation, preparation method of powder aerosol for inhalation and powder aerosol for inhalation 上海臣邦医药科技股份有限公司 2025-06-17 CN claimed
US-20250144021-A1 GEL FORMULATIONS FOR LOCAL DRUG RELEASE TECHNICAL UNIVERSITY OF DENMARK (DK) 2025-05-08 US claimed
WO-2025076059-A1 ROCAGLATE DERIVATIVES AND USES THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2025-04-10 WO claimed
EP-3943073-B1 BIODEGRADABLE POLYMER MICROPARTICLE CONTAINING STEROID-BASED DRUG AND PREPARATION METHOD THEREFOR REGENBIOTECH INC (KR) 2025-03-26 EP claimed
US-RE50218-E1 Non-steroidal anti-inflammatory ophthalmic compositions SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2024-11-26 US claimed
CN-118662643-A Application of hormone medicine composition in preparation of medicine for treating osteoarthritis 中南大学湘雅医院 2024-09-20 CN claimed
US-20240050632-A1 SELF-EXPANDING DEVICES AND METHODS THEREFOR INTERSECT ENT, INC 2024-02-15 US claimed
US-20240041935-A1 PREVENTION AND TREATMENT OF REPRODUCTIVE FAILURE BY REGENERATIVE CELLS AND ADJUVANTS CREATIVE MEDICAL TECHNOLOGIES, INC. (US) 2024-02-08 US claimed
US-11826494-B2 Self-expanding devices and methods therefor INTERSECT ENT, INC. (US) 2023-11-28 US claimed
EP-4013420-B1 METHOD OF BLOCKING OR AMELIORATING CYTOKINE RELEASE SYNDROME RIGEL PHARMACEUTICALS INC (US) 2023-11-01 EP claimed
EP-0786999-A1 COMBINATION METHOD FOR ACNE TREATMENT Merck & Co., Inc. (US) 1997-08-06 EP claimed
WO-1997015298-A1 COMBINATION OF LTD, RECEPTOR ANTAGONISTS WITH GLUCOCORTICOSTEROIDS BAYER AKTIENGESELLSCHAFT (DE) 1997-05-01 WO claimed
WO-1997009067-A1 COMBINATION OF 5-LIPOXYGENASE AND LEUKOTRIENE SYNTHESIS INHIBITORS WITH GLUCOCORTICOSTEROIDS BAYER AKTIENGESELLSCHAFT (DE) 1997-03-13 WO claimed
US-5543417-A 5 Alpha-reductase inhibitor and at least one of an antibacterial agent, a keratolytic agent or an anti-inflammatory agent MERCK & CO., INC. (US) 1996-08-06 US claimed
WO-1996012487-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 WO claimed
WO-1996012817-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 WO claimed
EP-0496520-A1 Novel bone acting agents MERCK & CO. INC. (US) 1992-07-29 EP claimed
US-4970206-A TRANSDERMAL DRUG DELIVERY MERCK & CO., INC. (US) 1990-11-13 US claimed
US-4765983-A INTESTINAL-SOLUBLE POLYMER AND MEDICAMENT YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1988-08-23 US claimed
US-4478818-A Ocular preparation housing steroid in two different therapeutic forms ALZA CORPORATION (US) 1984-10-23 US claimed