Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.55 |
| ▸ | ANPEP | P15144 | 6/20 | 0.55 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 4/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11019928 | 0.90 | DPP4 (0.67) | DPP4ANPEPNR1H2NR1H3KEAP1 | |
| SCHEMBL11018280 | 0.89 | DPP4 (0.56) | DPP4ANPEPNR1H2NR1H3LMNA | |
| SCHEMBL11017426 | 0.89 | DPP4 (0.66) | DPP4ANPEPKEAP1NFE2L2PARP1 | |
| SCHEMBL11018358 | 0.88 | DPP4 (0.55) | DPP4ANPEPNR1H2NR1H3CRHBP | |
| SCHEMBL11020653 | 0.86 | DPP4 (0.53) | DPP4ANPEPNR1H2NR1H3HTT | |
| SCHEMBL11018629 | 0.86 | DPP4 (0.53) | DPP4ANPEPNR1H2NR1H3CRHBP | |
| SCHEMBL11018644 | 0.86 | DPP4 (0.57) | DPP4ANPEPNR1H2NR1H3KEAP1 | |
| SCHEMBL11018426 | 0.83 | DPP4 (0.59) | DPP4ANPEPNR1H2NR1H3KEAP1 | |
| SCHEMBL11018036 | 0.83 | DPP4 (0.49) | DPP4ANPEPNR1H2NR1H3KEAP1 | |
| SCHEMBL11018476 | 0.83 | DPP4 (0.60) | DPP4ANPEPNR1H2NR1H3CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152021-A2 | Phthalimide derivatives, their preparation and their use as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | disclosed |