Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.59 |
| ▸ | ANPEP | P15144 | 3/20 | 0.59 |
| ▸ | PARP1 | P09874 | 6/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11017426 | 0.94 | DPP4 (0.66) | DPP4ANPEPPARP1PARP2LMNA | |
| SCHEMBL11019263 | 0.89 | DPP4 (0.60) | DPP4ANPEPLMNACRHBPCRHR2 | |
| SCHEMBL11018296 | 0.86 | DPP4 (0.56) | DPP4ANPEPLMNACRHBPCRHR2 | |
| SCHEMBL11018731 | 0.84 | DPP4 (0.53) | DPP4ANPEPPARP1PARP2LMNA | |
| SCHEMBL11016509 | 0.83 | DPP4 (0.55) | DPP4ANPEPPARP1PARP2LMNA | |
| SCHEMBL11022146 | 0.82 | DPP4 (0.68) | DPP4ANPEPLMNACRHBPCRHR2 | |
| SCHEMBL11022233 | 0.81 | DPP4 (0.63) | DPP4ANPEPHTTCRHBPCRHR2 | |
| SCHEMBL11018004 | 0.81 | DPP4 (0.47) | DPP4ANPEPPARP1PARP2LMNA | |
| SCHEMBL11020051 | 0.81 | DPP4 (0.66) | DPP4ANPEPLMNAHTTCRHBP | |
| SCHEMBL11019258 | 0.80 | DPP4 (0.48) | DPP4ANPEPHTTALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152021-A2 | Phthalimide derivatives, their preparation and their use as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | disclosed |