Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CDK1 | P06493 | 7/20 | 0.37 |
| ▸ | KDR | P35968 | 7/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10350458 | 0.99 | RAB9A (0.40) | RAB9ASMN1; SMN2ALDH1A1HSD17B10HPGD | |
| SCHEMBL11018052 | 0.92 | RAB9A (0.46) | RAB9ASMN1; SMN2ALDH1A1HSD17B10HPGD | |
| SCHEMBL11014559 | 0.91 | RAB9A (0.51) | RAB9ASMN1; SMN2ALDH1A1HSD17B10HPGD | |
| SCHEMBL11017215 | 0.91 | RAB9A (0.47) | RAB9ASMN1; SMN2ALDH1A1HSD17B10HPGD | |
| SCHEMBL11016174 | 0.90 | HSD17B10 (0.53) | RAB9ASMN1; SMN2ALDH1A1HSD17B10HPGD | |
| SCHEMBL11014013 | 0.90 | HSD17B10 (0.53) | RAB9ASMN1; SMN2ALDH1A1HSD17B10HPGD | |
| SCHEMBL11014920 | 0.90 | HSD17B10 (0.53) | RAB9ASMN1; SMN2ALDH1A1HSD17B10HPGD | |
| SCHEMBL11019536 | 0.90 | HSD17B10 (0.53) | RAB9ASMN1; SMN2ALDH1A1HSD17B10HPGD | |
| SCHEMBL11017823 | 0.90 | HSD17B10 (0.53) | RAB9ASMN1; SMN2ALDH1A1HSD17B10HPGD | |
| SCHEMBL11018451 | 0.90 | HSD17B10 (0.53) | RAB9ASMN1; SMN2ALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0158137-A2 | Pyrimidines | MERCK PATENT GmbH (DE) | 1985-10-16 | — | — | EP | disclosed |