Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | TACR2 | P21452 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SHBG | P04278 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11015800 | 0.94 | HSD17B10 (0.51) | KDM4ERAB9AHSD17B10TSHRALDH1A1 | |
| SCHEMBL11017540 | 0.92 | KDM4E (0.49) | KDM4ERAB9AHSD17B10TSHRALDH1A1 | |
| SCHEMBL11015834 | 0.92 | KDM4E (0.49) | KDM4ERAB9AHSD17B10TSHRALDH1A1 | |
| SCHEMBL11013515 | 0.92 | KDM4E (0.49) | KDM4ERAB9AHSD17B10TSHRALDH1A1 | |
| SCHEMBL4950076 | 0.92 | KCNH2 (0.39) | KDM4ERAB9AHSD17B10TSHRALDH1A1 | |
| SCHEMBL4948080 | 0.92 | KCNH2 (0.39) | KDM4ERAB9AHSD17B10TSHRALDH1A1 | |
| SCHEMBL4949286 | 0.92 | KCNH2 (0.41) | KDM4ERAB9AHSD17B10TSHRALDH1A1 | |
| SCHEMBL4947793 | 0.92 | KCNH2 (0.41) | KDM4ERAB9AHSD17B10TSHRALDH1A1 | |
| SCHEMBL4950539 | 0.92 | KCNH2 (0.41) | KDM4ERAB9AHSD17B10TSHRALDH1A1 | |
| SCHEMBL4949276 | 0.90 | KCNH2 (0.40) | KDM4ERAB9AHSD17B10TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0144013-A2 | Thienothiophene derivatives | MERCK PATENT GmbH (DE) | 1985-06-12 | — | — | EP | disclosed |