Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4947793 | 0.98 | KCNH2 (0.41) | KCNH2CYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL4950539 | 0.98 | KCNH2 (0.41) | KCNH2CYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL4949286 | 0.98 | KCNH2 (0.41) | KCNH2CYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL2768137 | 0.95 | KCNH2 (0.39) | KCNH2CYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL4948080 | 0.95 | KCNH2 (0.39) | KCNH2CYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL4950076 | 0.95 | KCNH2 (0.39) | KCNH2CYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL2767901 | 0.95 | KCNH2 (0.39) | KCNH2CYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL5353884 | 0.95 | KCNH2 (0.39) | KCNH2CYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL2247644 | 0.95 | KCNH2 (0.39) | KCNH2CYP2E1CYP3A4CYP2A6CYP2C9 | |
| SCHEMBL10015617 | 0.95 | KCNH2 (0.39) | KCNH2CYP2E1CYP3A4CYP2A6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188670-A1 | 1,4-Dithienylbenzene Derivative | NAT. INST. OF ADVANCED INDUSTRIAL SCI. AND TECH. (JP) | 2008-08-07 | — | — | US | disclosed |
| US-20080188670-A1 | 1,4-Dithienylbenzene Derivative | NAT. INST. OF ADVANCED INDUSTRIAL SCI. AND TECH. (JP) | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188670-A1 | 1,4-Dithienylbenzene Derivative | SLC22A4, SLC19A2, SLC22A1 | KCNH2 1058/4885CYP2E1 661/4885CYP3A4 1051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.