Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.56 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.46 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | PPARD | Q03181 | 7/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3661831 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL7640632 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL6836310 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL3033182 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL7504525 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL2531077 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL992668 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL1312624 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL10704488 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL9629897 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150230-A1 | Inhibitors for acid gas conditioning solutions | THE DOW CHEMICAL COMPANY (US) | 1985-08-07 | — | — | EP | disclosed |
| US-4431563-A | AQUEOUS ALKANOLAMINES CONTAINING AN AMMONIUM OR METAL THIOCYANATE; CORROSION RESISTANCE | THE DOW CHEMICAL COMPANY (US) | 1984-02-14 | — | — | US | disclosed |
| US-3959362-A | Ammonium mercaptoalkanesulfonate salts, their preparation, photographic fixing solutions containing same, and method of fixing photographic film therewith | EASTMAN KODAK COMPANY (US) | 1976-05-25 | — | — | US | disclosed |