Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.56 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.46 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | PPARD | Q03181 | 7/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11017002 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL3661831 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL7640632 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL6836310 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL7504525 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL2531077 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL992668 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL1312624 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL10704488 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1MEN1 | |
| SCHEMBL9629897 | 1.00 | SPHK2 (0.56) | SPHK2SPHK1CES2CES1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2255377-A | — | — | None | — | — | JP | disclosed |
| CN-117321042-A | Oxodihydro indole compounds for the treatment of inflammatory diseases or cancers | 豪夫迈·罗氏有限公司 | 2023-12-29 | — | — | CN | disclosed |
| US-8802713-B2 | 3-alkoxy-1-phenylpyrazole derivatives and pesticides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-08-12 | — | — | US | disclosed |
| EP-2202226-B1 | 3-ALKOXY-1-PHENYLPYRAZOLE DERIVATIVE AND PEST CONTROL AGENT | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2013-06-05 | — | — | EP | disclosed |
| US-20100210704-A1 | 3-ALKOXY-1-PHENYLPYRAZOLE DERIVATIVES AND PESTICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-08-19 | — | — | US | disclosed |
| EP-2202226-A1 | 3-ALKOXY-1-PHENYLPYRAZOLE DERIVATIVE AND PEST CONTROL AGENT | Kumiai Chemical Industry CO., LTD. (JP) | 2010-06-30 | — | — | EP | disclosed |
| CN-101282737-A | Herbal pharmaceutical composition for cartilage tissue regeneration and osteoarthritis treatment | KOREA MEDICAL SCIENCE INST (KR) | 2008-10-08 | — | — | CN | disclosed |
| WO-2007007958-A1 | HERBAL PHARMACEUTICAL COMPOSITION FOR REGENERATIVE AGENT OF CARTILAGINOUS TISSUE AND TREATMENT OF OSTEOARTHRITIS | YUHAN CORPORATION (KR) | 2007-01-18 | — | — | WO | disclosed |
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |
| JP-H02255377-A | THERMAL RECORDING MATERIAL | FUJI PHOTO FILM CO LTD | 1990-10-16 | — | — | JP | disclosed |
| US-4918122-A | CONTAINING REACTION PRODUCT OF ORGANIC PHOSPHONATE AND (THIO)AMIDE | CIBA-GEIGY CORPORATION (US) | 1990-04-17 | — | — | US | disclosed |
| US-3959362-A | Ammonium mercaptoalkanesulfonate salts, their preparation, photographic fixing solutions containing same, and method of fixing photographic film therewith | EASTMAN KODAK COMPANY (US) | 1976-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210704-A1 | 3-ALKOXY-1-PHENYLPYRAZOLE DERIVATIVES AND PESTICIDES | HCN3, HCN4, KCNH3 | SPHK2 1383/4885SPHK1 1257/4885CES2 773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.