Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | RARB | P10826 | 9/20 | 0.44 |
| ▸ | RARA | P10276 | 2/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11014013 | 1.00 | HSD17B10 (0.53) | HSD17B10TSHRRAB9ASMN1; SMN2MAPT | |
| SCHEMBL11016174 | 1.00 | HSD17B10 (0.53) | HSD17B10TSHRRAB9ASMN1; SMN2MAPT | |
| SCHEMBL11018451 | 1.00 | HSD17B10 (0.53) | HSD17B10TSHRRAB9ASMN1; SMN2MAPT | |
| SCHEMBL11017823 | 1.00 | HSD17B10 (0.53) | HSD17B10TSHRRAB9ASMN1; SMN2MAPT | |
| SCHEMBL11019536 | 1.00 | HSD17B10 (0.53) | HSD17B10TSHRRAB9ASMN1; SMN2MAPT | |
| SCHEMBL11014920 | 1.00 | HSD17B10 (0.53) | HSD17B10TSHRRAB9ASMN1; SMN2MAPT | |
| SCHEMBL11017580 | 0.99 | RAB9A (0.54) | HSD17B10TSHRRAB9ASMN1; SMN2MAPT | |
| SCHEMBL11016553 | 0.99 | RAB9A (0.54) | HSD17B10TSHRRAB9ASMN1; SMN2MAPT | |
| SCHEMBL11016416 | 0.99 | RAB9A (0.54) | HSD17B10TSHRRAB9ASMN1; SMN2MAPT | |
| SCHEMBL11018963 | 0.99 | RAB9A (0.54) | HSD17B10TSHRRAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0158137-A2 | Pyrimidines | MERCK PATENT GmbH (DE) | 1985-10-16 | — | — | EP | disclosed |