Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD44 | P16070 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10072631 | 0.87 | CYP3A4 (0.55) | CD44CYP3A4TSHRMAPK1ALDH1A1 | |
| SCHEMBL10072636 | 0.87 | CYP3A4 (0.55) | CD44CYP3A4TSHRMAPK1ALDH1A1 | |
| SCHEMBL6153206 | 0.83 | PTK2 (0.44) | CD44CYP3A4TSHRMAPK1ALDH1A1 | |
| SCHEMBL20160730 | 0.80 | ESR1 (0.35) | ALDH1A1CYP1A2HSD17B10TDP1KDM4E | |
| SCHEMBL6983173 | 0.79 | TSHR (0.50) | CD44CYP3A4TSHRMAPK1ALDH1A1 | |
| SCHEMBL21154376 | 0.78 | PTK2 (0.47) | CD44CYP3A4ALDH1A1PRKCIALOX15 | |
| SCHEMBL5084584 | 0.77 | PRKCI (0.46) | CYP3A4TSHRMAPK1ALDH1A1PRKCI | |
| Hydrochloric Acid SCHEMBL11754014 | 0.77 | TSHR (0.48) | CD44CYP3A4TSHRMAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11754022 | 0.77 | TSHR (0.48) | CD44CYP3A4TSHRMAPK1ALDH1A1 | |
| SCHEMBL21593666 | 0.75 | CYP3A4 (0.32) | CYP3A4TSHRMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0146350-A2 | Hair treatment composition | UNILEVER PLC (GB) | 1985-06-26 | — | — | EP | claimed |
| EP-0146350-A2 | Hair treatment composition | UNILEVER PLC (GB) | 1985-06-26 | — | — | EP | disclosed |