SCHEMBL11017789

SCHEMBL11017789

CCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(=O)NC(CC(C)C)C(O)CC(=O)N[C@H](CO)C(C)CC

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11017795 1.00 REN (0.66) REN
SCHEMBL10724083 0.96 REN (0.61) REN
SCHEMBL10724089 0.96 REN (0.61) REN
SCHEMBL10722650 0.93 REN (0.58) REN
SCHEMBL10722656 0.93 REN (0.58) REN
SCHEMBL10723643 0.93 REN (0.57) REN
SCHEMBL10723633 0.93 REN (0.57) REN
SCHEMBL10720944 0.93 REN (0.71) REN
SCHEMBL10720957 0.93 REN (0.71) REN
SCHEMBL10723989 0.92 REN (0.65) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0152255-A2 New renin-inhibitory peptides and their use SANKYO COMPANY LIMITED (JP) 1985-08-21 — — EP disclosed
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