Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.54 |
| ▸ | ANPEP | P15144 | 5/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11020782 | 0.84 | DPP4 (0.57) | DPP4ANPEPNR1H2NR1H3NLRP3 | |
| SCHEMBL11019371 | 0.83 | DPP4 (0.54) | DPP4ANPEPNR1H2NR1H3DDB1 | |
| SCHEMBL11018821 | 0.82 | DPP4 (0.55) | DPP4ANPEPNR1H2NR1H3NLRP3 | |
| SCHEMBL11020002 | 0.81 | DPP4 (0.62) | DPP4ANPEPNR1H2NR1H3TYMS | |
| SCHEMBL11016230 | 0.80 | DPP4 (0.61) | DPP4ANPEPNR1H2NR1H3KDM4E | |
| SCHEMBL11018073 | 0.79 | DPP4 (0.60) | DPP4ANPEPNR1H2NR1H3KDM4E | |
| SCHEMBL11018532 | 0.79 | DPP4 (0.60) | DPP4ANPEPNR1H2NR1H3 | |
| SCHEMBL11022219 | 0.79 | DPP4 (0.60) | DPP4ANPEPNR1H2NR1H3KDM4E | |
| SCHEMBL11018141 | 0.79 | NLRP3 (0.52) | DPP4ANPEPNR1H2NR1H3NLRP3 | |
| SCHEMBL11018878 | 0.78 | DPP4 (0.59) | DPP4ANPEPNR1H2NR1H3DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152021-A2 | Phthalimide derivatives, their preparation and their use as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | disclosed |