Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.51 |
| ▸ | ANPEP | P15144 | 5/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11018358 | 0.91 | DPP4 (0.55) | DPP4ANPEPCRHBPCRHR2NR1H2 | |
| SCHEMBL11021544 | 0.90 | DPP4 (0.52) | DPP4ANPEPCRHBPCRHR2CTDSP1 | |
| SCHEMBL11016927 | 0.87 | ANPEP (0.49) | DPP4ANPEPCRHBPCRHR2ELANE | |
| SCHEMBL11019989 | 0.87 | DPP4 (0.49) | DPP4ANPEPCRHBPCRHR2ALOX15 | |
| SCHEMBL11020051 | 0.87 | DPP4 (0.66) | DPP4ANPEPCRHBPCRHR2CTDSP1 | |
| SCHEMBL11022166 | 0.85 | ANPEP (0.45) | DPP4ANPEPCRHBPCRHR2 | |
| SCHEMBL11022123 | 0.84 | DPP4 (0.55) | DPP4ANPEPCRHBPCRHR2ELANE | |
| SCHEMBL11021844 | 0.83 | ALDH1A1 (0.47) | DPP4ANPEPMAPK1 | |
| SCHEMBL11016555 | 0.82 | DPP4 (0.56) | DPP4ANPEPCRHBPCRHR2HSD17B10 | |
| SCHEMBL11019777 | 0.82 | DPP4 (0.52) | DPP4ANPEPNR1H2NR1H3CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152021-A2 | Phthalimide derivatives, their preparation and their use as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | disclosed |