Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.65 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.62 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11021483 | 0.85 | GRIN1 (0.63) | EGFRGRIN1GRIN2BALDH1A1KDM4E | |
| SCHEMBL11019881 | 0.82 | EGFR (0.59) | EGFRALDH1A1TSHRSMN1; SMN2MAPT | |
| SCHEMBL11019684 | 0.81 | EGFR (0.69) | EGFRGRIN1GRIN2BALDH1A1HIF1A | |
| SCHEMBL11023598 | 0.77 | KMT2A (0.60) | EGFRALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL28614894 | 0.76 | BLM (0.62) | ALDH1A1KDM4ESMN1; SMN2MAPTLMNA | |
| SCHEMBL12123805 | 0.75 | KMT2A (0.73) | EGFRALDH1A1MAPTLMNAHTT | |
| SCHEMBL3361764 | 0.74 | MEN1 (0.47) | EGFRALDH1A1TSHRHIF1ASMN1; SMN2 | |
| SCHEMBL8879210 | 0.74 | SMN1; SMN2 (0.73) | EGFRALDH1A1KDM4ESMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL7932179 | 0.74 | KMT2A (0.75) | EGFRALDH1A1MAPTLMNAHTT | |
| Hydrochloric Acid SCHEMBL8842314 | 0.74 | SMN1; SMN2 (0.60) | ALDH1A1KDM4ETSHRHIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0156785-A1 | 2-(Aminoalkyl)-acrylophenones, their preparation and their use | S.A.R.L. GALEPHAR (FR) | 1985-10-02 | — | — | EP | claimed |
| EP-0156785-A1 | 2-(Aminoalkyl)-acrylophenones, their preparation and their use | S.A.R.L. GALEPHAR (FR) | 1985-10-02 | — | — | EP | disclosed |