Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.64 |
| ▸ | ANPEP | P15144 | 4/20 | 0.64 |
| ▸ | AHR | P35869 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11019049 | 0.82 | AHR (0.53) | DPP4ANPEPAHRMAOADDB1 | |
| SCHEMBL11018379 | 0.81 | AHR (0.63) | DPP4ANPEPAHRMAOADDB1 | |
| SCHEMBL11017617 | 0.80 | DPP4 (0.68) | DPP4ANPEPAHRNR1H2NR1H3 | |
| SCHEMBL11016329 | 0.79 | DPP4 (0.60) | DPP4ANPEPAHRNR1H2NR1H3 | |
| SCHEMBL11019780 | 0.79 | DPP4 (0.62) | DPP4ANPEPAHRMAOANR1H2 | |
| SCHEMBL11018214 | 0.78 | DPP4 (0.74) | DPP4ANPEPNR1H2NR1H3 | |
| SCHEMBL11020919 | 0.78 | DPP4 (0.65) | DPP4ANPEPNR1H2NR1H3ALDH1A1 | |
| SCHEMBL10878219 | 0.77 | DPP4 (0.68) | DPP4ANPEPNR1H2NR1H3ALDH1A1 | |
| SCHEMBL11018850 | 0.77 | DPP4 (0.51) | DPP4ANPEPNR1H2NR1H3HSD17B10 | |
| SCHEMBL11021461 | 0.77 | DPP4 (0.64) | DPP4ANPEPNR1H2NR1H3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0152021-A2 | Phthalimide derivatives, their preparation and their use as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | disclosed |