SCHEMBL11019130

SCHEMBL11019130

O=C(O)CC1=NCC(=O)N1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.35
GABRA5 P31644 2/20 0.35
GABRB2 P47870 2/20 0.35
GABRG2 P18507 1/20 0.35
GABRB3 P28472 1/20 0.35
GABRA3 P34903 1/20 0.35
GABRA2 P47869 1/20 0.35
ITGB3 P05106 1/20 0.32
ITGB2 P05107 1/20 0.32
ITGB1 P05556 1/20 0.32
ITGAV P06756 1/20 0.32
ITGA2B P08514 1/20 0.32
ITGA5 P08648 1/20 0.32
ITGB5 P18084 1/20 0.32
ITGAL P20701 1/20 0.32
ADAMTS5 Q9UNA0 1/20 0.31
TSHR P16473 2/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31
NFKB1 P19838 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9134340 0.67
SCHEMBL1713883 0.67 DAO (0.32) GABRA1GABRA5GABRB2GABRG2GABRB3
Hydrochloric Acid SCHEMBL11625324 0.62 NISCH (0.47) TSHRALDH1A1KDM4E
SCHEMBL5590875 0.58 ITGB3 (0.32) GABRA1GABRA5GABRB2ITGB3ITGB2
SCHEMBL29414131 0.58 AKR1B1 (0.39) GABRA1GABRA5GABRB2TSHRALDH1A1
SCHEMBL13185779 0.58
Nitrilotriacetic Acid SCHEMBL28649427 0.57 CRBN (0.50) ITGB3ITGB2ITGB1ITGAVITGA2B
Nitrilotriacetic Acid SCHEMBL27910005 0.57 CRBN (0.50) ITGB3ITGB2ITGB1ITGAVITGA2B
Succinic Acid SCHEMBL436244 0.56 CRBN (0.58) ITGB3ITGB2ITGB1ITGAVITGA2B
Succinimide SCHEMBL9241351 0.56 CRBN (0.58) ITGB3ITGB2ITGB1ITGAVITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0048834-B1 METHOD FOR MEASUREMENT OF TRACE ENZYMES FUJI PHOTO FILM CO., LTD. (JP) 1985-06-19 EP disclosed
EP-0047470-B1 METHOD FOR IMMUNOCHEMICAL MEASUREMENT FUJI PHOTO FILM CO., LTD. (JP) 1985-04-24 EP disclosed
US-4473652-A LABELLING WITH CYANINE OR MEROCYANINE DYE FUJI PHOTO FILM CO., LTD. (JP) 1984-09-25 US disclosed
US-4414325-A PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 1983-11-08 US disclosed
EP-0048834-A1 Method for measurement of trace enzymes FUJI PHOTO FILM CO., LTD. (JP) 1982-04-07 EP disclosed
EP-0047470-A1 Method for immunochemical measurement FUJI PHOTO FILM CO., LTD. (JP) 1982-03-17 EP disclosed