Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.69 |
| ▸ | CES2 | O00748 | 3/20 | 0.52 |
| ▸ | CES1 | P23141 | 3/20 | 0.52 |
| ▸ | ABL1 | P00519 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4805251 | 0.98 | EGFR (0.70) | EGFRCES2CES1ABL1MAOA | |
| SCHEMBL15245115 | 0.91 | EGFR (0.81) | EGFRCES2CES1ABL1SRC | |
| SCHEMBL6223672 | 0.82 | EGFR (0.69) | EGFRCES2CES1ABL1MAOA | |
| SCHEMBL6222039 | 0.82 | EGFR (0.69) | EGFRCES2CES1ABL1MAOA | |
| SCHEMBL9682567 | 0.81 | EGFR (1.00) | EGFRCES2CES1ABL1SRC | |
| Hydrochloric Acid SCHEMBL4810682 | 0.81 | EGFR (0.70) | EGFRCES2CES1ABL1MAOA | |
| Hydrochloric Acid SCHEMBL4803436 | 0.81 | EGFR (0.70) | EGFRCES2CES1ABL1MAOA | |
| Hydrochloric Acid SCHEMBL4799828 | 0.80 | EGFR (1.00) | EGFRCES2CES1ABL1SRC | |
| SCHEMBL11023097 | 0.79 | EGFR (0.65) | EGFRCES2CES1ABL1SRC | |
| SCHEMBL8132385 | 0.77 | ALDH1A1 (0.61) | CES2CES1GAACYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0156785-A1 | 2-(Aminoalkyl)-acrylophenones, their preparation and their use | S.A.R.L. GALEPHAR (FR) | 1985-10-02 | — | — | EP | claimed |
| EP-0156785-A1 | 2-(Aminoalkyl)-acrylophenones, their preparation and their use | S.A.R.L. GALEPHAR (FR) | 1985-10-02 | — | — | EP | disclosed |