Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TXN | P10599 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10764336 | 0.85 | KMT2A (0.67) | SMN1; SMN2KMT2APOLBMEN1MAPT | |
| SCHEMBL9304496 | 0.78 | SMN1; SMN2 (0.65) | SMN1; SMN2KMT2APOLBMEN1MAPT | |
| SCHEMBL10894311 | 0.78 | SMN1; SMN2 (0.68) | SMN1; SMN2KMT2APOLBMEN1LMNA | |
| SCHEMBL9304705 | 0.78 | KMT2A (0.67) | SMN1; SMN2KMT2APOLBMAPTLMNA | |
| SCHEMBL757400 | 0.76 | KMT2A (0.67) | SMN1; SMN2KMT2APOLBMAPTLMNA | |
| SCHEMBL9308094 | 0.75 | SMN1; SMN2 (0.57) | SMN1; SMN2KMT2APOLBMEN1MAPT | |
| SCHEMBL10641547 | 0.74 | KMT2A (0.62) | SMN1; SMN2KMT2APOLBMAPTLMNA | |
| SCHEMBL10639826 | 0.73 | SMN1; SMN2 (0.58) | SMN1; SMN2KMT2APOLBMEN1MAPT | |
| SCHEMBL11019180 | 0.73 | SMN1; SMN2 (0.58) | SMN1; SMN2KMT2APOLBMEN1MAPT | |
| SCHEMBL11121930 | 0.73 | SMN1; SMN2 (0.73) | SMN1; SMN2KMT2APOLBMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161219-A2 | Heterocyclic mercaptocarboxylic-acid esters and anhydrides as corrosion inhibiting agents | CIBA-GEIGY AG (CH) | 1985-11-13 | — | — | EP | disclosed |