SCHEMBL757400

SCHEMBL757400

O=C(O)CC(Sc1nc2ccccc2[nH]1)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.67
SMN1; SMN2 Q16637 3/20 0.66
POLB P06746 2/20 0.55
ALDH1A1 P00352 1/20 0.54
LMNA P02545 3/20 0.54
NPC1 O15118 4/20 0.50
RAB9A P51151 4/20 0.50
BCHE P06276 1/20 0.50
HPGD P15428 1/20 0.49
EPHX2 P34913 1/20 0.49
MAPT P10636 1/20 0.48
HSD17B10 Q99714 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10641547 0.89 KMT2A (0.62) KMT2ASMN1; SMN2POLBLMNANPC1
SCHEMBL8973070 0.88 KMT2A (0.63) KMT2ASMN1; SMN2POLBALDH1A1LMNA
SCHEMBL10872581 0.87 POLB (0.70) KMT2ASMN1; SMN2POLBALDH1A1LMNA
SCHEMBL10645047 0.87 SMN1; SMN2 (0.61) KMT2ASMN1; SMN2POLBALDH1A1LMNA
SCHEMBL10641582 0.87 SMN1; SMN2 (0.61) KMT2ASMN1; SMN2POLBALDH1A1LMNA
SCHEMBL10764336 0.87 KMT2A (0.67) KMT2ASMN1; SMN2POLBALDH1A1LMNA
SCHEMBL9304705 0.87 KMT2A (0.67) KMT2ASMN1; SMN2POLBLMNANPC1
SCHEMBL8972983 0.87 SMN1; SMN2 (0.60) KMT2ASMN1; SMN2POLBLMNANPC1
SCHEMBL9305881 0.85 KMT2A (0.61) KMT2ASMN1; SMN2POLBALDH1A1LMNA
SCHEMBL754927 0.85 SMN1; SMN2 (0.65) KMT2ASMN1; SMN2POLBALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8450931-B2 Process for minimizing electromigration in an electronic device DOW CORNING CORPORATION (US) 2013-05-28 US claimed
EP-1880416-B1 PROCESS FOR MINIMIZING ELECTROMIGRATION IN AN ELECTRONIC DEVICE DOW CORNING (US) 2012-01-18 EP claimed
US-7723425-B2 Pigment compositions with modified ATRP copolymer dispersants CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US claimed
US-20080054806-A1 Process for Minimizing Electromigration in an Electronic Device DOW CORNING CORPORATION 2008-03-06 US claimed
EP-1880416-A1 PROCESS FOR MINIMIZING ELECTROMIGRATION IN AN ELECTRONIC DEVICE Dow Corning Corporation (US) 2008-01-23 EP claimed
WO-2006122025-A1 PROCESS FOR MINIMIZING ELECTROMIGRATION IN AN ELECTRONIC DEVICE DOW CORNING CORPORATION (US) 2006-11-16 WO claimed
EP-0372405-A2 Corrosion inhibitive pretreatment for \"copper-free\" mirrors PPG INDUSTRIES, INC. (US) 1990-06-13 EP claimed
EP-1465935-B1 PIGMENT COMPOSITIONS WITH MODIFIED ATRP COPOLYMER DISPERSANTS BASF SE (DE) 2016-09-07 EP disclosed
US-8450931-B2 Process for minimizing electromigration in an electronic device DOW CORNING CORPORATION (US) 2013-05-28 US disclosed
EP-1611197-B1 LIGHT STABILISING POLYMER DISPERSANTS IN PIGMENT DISPERSIONS BASF SE (DE) 2012-03-21 EP disclosed
EP-1880416-B1 PROCESS FOR MINIMIZING ELECTROMIGRATION IN AN ELECTRONIC DEVICE DOW CORNING (US) 2012-01-18 EP disclosed
US-7723425-B2 Pigment compositions with modified ATRP copolymer dispersants CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US disclosed
US-7723425-B2 Pigment compositions with modified ATRP copolymer dispersants CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US disclosed
US-20080054806-A1 Process for Minimizing Electromigration in an Electronic Device DOW CORNING CORPORATION 2008-03-06 US disclosed
EP-1880416-A1 PROCESS FOR MINIMIZING ELECTROMIGRATION IN AN ELECTRONIC DEVICE Dow Corning Corporation (US) 2008-01-23 EP disclosed
WO-2006122025-A1 PROCESS FOR MINIMIZING ELECTROMIGRATION IN AN ELECTRONIC DEVICE DOW CORNING CORPORATION (US) 2006-11-16 WO disclosed
US-20060229407-A1 Light stabilising polymer dispersants in pigment dispersions CIBA SPECIALTY CHEMICALS CORP. 2006-10-12 US disclosed
US-5008153-A Corrosion inhibitive pretreatment for \"copper-free\" mirrors PPG INDUSTRIES, INC. (US) 1991-04-16 US disclosed
EP-0372405-A2 Corrosion inhibitive pretreatment for \"copper-free\" mirrors PPG INDUSTRIES, INC. (US) 1990-06-13 EP disclosed
US-4873346-A BRONCHODILATORS, TREATMENT OF ASTHMA THE UPJOHN COMPANY (US) 1989-10-10 US disclosed