Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11022797 | 0.88 | HTR1B (0.55) | HTR1BKDM4EHRH1HTR7 | |
| SCHEMBL11018350 | 0.88 | KDM4E (0.56) | HTR1BKDM4EHRH1HTR7ALDH1A1 | |
| SCHEMBL12603016 | 0.85 | HTR1B (0.61) | HTR1BKDM4EHRH1HTR7ALDH1A1 | |
| SCHEMBL11019533 | 0.84 | KDM4E (0.58) | HTR1BKDM4EHRH1HTR7ALDH1A1 | |
| SCHEMBL11023153 | 0.81 | ALDH1A1 (0.43) | HTR1BKDM4EALDH1A1 | |
| SCHEMBL11019776 | 0.81 | HTR1B (0.46) | HTR1BKDM4EALDH1A1 | |
| SCHEMBL11021382 | 0.81 | HTR1B (0.50) | HTR1BKDM4EHRH1HTR7ALDH1A1 | |
| SCHEMBL11021244 | 0.79 | KDM4E (0.59) | HTR1BKDM4EHRH1HTR7ALDH1A1 | |
| SCHEMBL31028996 | 0.78 | HTR1B (0.58) | HTR1BKDM4EHRH1ALDH1A1 | |
| SCHEMBL13948841 | 0.78 | HRH1 (0.63) | HTR1BHRH1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0157652-A1 | 2-, 3- And 4-biphenyloxyaminoalkanes and related compounds, their preparation and uses, and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1985-10-09 | — | — | EP | disclosed |