Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11021326 | 0.86 | MAPT (0.42) | TSHRTDP1KDM4EMEN1KMT2A | |
| SCHEMBL11022028 | 0.83 | MAPT (0.40) | KDM4EMEN1KMT2AMAPTHPGD | |
| SCHEMBL11022531 | 0.78 | USP8 (0.30) | — | |
| SCHEMBL11021465 | 0.75 | GAA (0.39) | MAPT | |
| SCHEMBL7537860 | 0.69 | — | — | |
| SCHEMBL5150808 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL27560191 | 0.67 | NOS1 (0.48) | TSHRKDM4EMAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL5537146 | 0.66 | KDM4E (0.34) | KDM4EMAPTHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL31016936 | 0.65 | — | — | |
| SCHEMBL11020657 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0160818-A1 | Thiazole derivatives | BASF Aktiengesellschaft (DE) | 1985-11-13 | — | — | EP | disclosed |